Ganoderma 365

Ganoderma 365

Ganoderma Lucidum, crowned “King of Herbs” by China’s Yellow Emperor over five thousand years ago, is globally recognized today as one of the most beneficial mushrooms ever discovered.  Mounting research documents Ganoderma Lucidum’s astonishing journey from exotic fungus to champion of hope for a healthy life.  Today Ganoderma Lucidum (called Reishi in Japan and Ling Zhi in China) is well-known and is becoming a household term as word spreads of its remarkable ability to:

  • • Support the Immune System
  • • Oxygenate the Body
  • • Boost Energy
  • • Support Blood Circulation
  • • Promote Cell Rejuvenation
  • • Detoxify the Body
  • • Support Restful Sleep
  • • Promote Sexual Stamina

In general, Ganoderma Lucidum is considered one of the most potent adaptogens available. Adaptogens are those herbs and substances that increase the body’s resistance to stress and empower it to overcome all health challenges more quickly.  Over 150 antioxidants may account for some of the adaptogenic benefits.  However, Ganoderma Lucidum is also rich in more than 125 beneficial and highly researched triterpenes like ganoderic acid and many powerful trace minerals like germanium (one of the best transmitters of negative ions needed for cellular protection).  Ganoderma Lucidum is likewise a remarkable source of well-known polysaccharides like beta glucan (with profound benefits for the immune system), and other substances like coumarin, mannitol, and a variety of alkaloids that benefit a diversity of metabolic systems.  It’s no wonder Ganoderma Lucidum is so highly regarded!

While the benefits of Ganoderma Lucidum are widely accepted, there’s a lot of confusion today from all the marketing claims on the Internet about what form of Ganoderma Lucidum is best to use. Many say it’s best to use Ganoderma extracted from the fruiting body, while others favor Ganoderma extracted from the mycelium, and some market cracked Ganoderma spore.  Then there’s the discussion about whether to use hot water or alcohol extraction methods.  Finally, there’s a lot said about whether the extraction should be standardized for some particular compound.  These are all important considerations, and they should be answered based on scientific fact, not historical usage or someone’s opinion.  Obviously, there’s a lot of amazingly complex bio-chemistry going on in Ganoderma Lucidum and that’s precisely why it is so valued for its health-promoting potential. Furthermore, it seems that regardless of how we abuse Ganoderma Lucidum with harsh extraction processes, some benefits remain intact.  We have accurately addressed these issues here so you can decide which Ganoderma Lucidum is best for your personal consumption.

Definitions, Explanations & Clarifications
You may be wondering what some of the words used above really mean.  So first, let’s start with some definitions that will help clarify everything.

Fruiting Body – this is any mushroom you see growing out of the ground, a dead tree or a bag of sterilized sawdust. This is the reproductive part of the organism – much like the flower of a plant. And just like flowers only bloom during a certain season, the mushroom fruiting body will only form in response to some stress (extreme heat/cold, excess moisture, or loss of nutrition in the environment) that forces the organism into a “reproduce or die” mode. In other words, the fruiting body is NOT the growth form of the mushroom organism. It is strictly the reproductive part of the fungus produced at the end of its life cycle once most of the beneficial compounds are depleted.

Mycelium – this is the growth form of the organism where all of the life processes occur – including formation of antibiotic, antifungal and antiviral compounds.  Quality mycelium should be cultivated in an organic substrate (nutrient broth) that provides everything required for the mycelium to flourish –nutrition, moisture, etc.  Most mushroom-derived compounds used in pharmaceuticals are NOT actually collected from the mycelium itself, but from the nutrient broth or substrate where mycelium grows.

Spore – the equivalent of a seed, the spore is produced by the fruiting body as the final part of the reproductive process.  While the spore contains the genetic material capable of producing the mycelium and the subsequent fruiting body, it does not contain all of the benefits of either the mycelium or the fruiting body any more than a seed from a lemon provides all the benefits of a lemon or even a lemon tree.  Furthermore the spore develops a nearly impenetrable shell to protect the genetic material and the lubricating oily essence.  To access the genetic material or the oily essence (promoted by some companies), the spore must be cracked and processed and any benefits are completely minimized.

Extract – a word that covers a lot of possibilities. Derived from either the fruiting body or the mycelium using some type of solvent, extractions supposedly concentrate some desirable compound(s) while destroying, eliminating or reducing other portions of the fungus. The two most common solvents used for extraction are alcohol and boiling water. The widely held belief that extracts are somehow “more potent” than other forms of mushroom material is simply false.  Such narrow thinking is the result of historical usage and misleading Internet marketing claims.  Science provides definitive evidence that only Fully Potentiated Ganoderma Lucidum provides all of the wholesome goodness people need and deserve.

Fully Potentiated Ganoderma Lucidum – the complete fungal material consisting of all the biologically active components produced throughout the entire life cycle of the organism – 365 days a year.  These compounds are responsible for the antibiotic, antiviral and antifungal properties (and all the other ‘survival’ compounds) that the fungus produces to give itself an advantage over highly competitive bacteria and microbes. These secondary metabolites have opened up the frontiers of medicine, with such breakthroughs as antibiotics from penicillin mold and cholesterol lowering drugs from other fungi.   It is precisely these extraordinary properties that are removed through most extraction processes.  Only in the 21st century has science developed practical ways to reliably produce fully potentiated Ganoderma Lucidum now considered the “Gold Standard” for Ganoderma Lucidum-based dietary supplements (Dr. Solomon Wasser: Medicinal Properties of substances occurring in Higher Basidiomycetes Mushrooms: Current Perspectives (Review) [pdf] published in – International Journal of Medicinal Mushrooms.

The Process In Detail
Mushrooms belong to the Kingdom of Fungi. Science has long known that all fungi produce potent bioactive compounds.  A classic example of medicines derived from fungi is antibiotics – some 99% started as fungi. Nearly all of the research done since the discovery of Penicillin, the first fungal antibiotic, in 1928 has shown that the primary bio-active compounds are the extra-cellular ones.  These are the compounds that are released out of the cells and into the immediate environment or substrate that is nurturing the growing mycelium. These same compounds in turn digest the fungal foods and transport the nutrients back across the cell wall where they are used by the fungi to protect themselves from bacteria and other microbes.  Over the life span of a fungus, fully 95% of all the bioactive compounds produced are excreted out of its cells and into their surrounding substrate in which the fungus was grown.

In contrast, the mushroom fruiting body is the spent or used up fungal tissue that appears at the very tail end of the mushroom’s life span and typically has the lowest concentration of bioactive compounds present.  The mycelium is the growing portion of the fungi and contains a much higher proportion of the extra-cellular bioactive metabolites, but far fewer than those found in the substrate.

To realize the full potential of Ganoderma Lucidum, it is important to capture all of the different classes of compounds produced during the entire life cycle. This includes the cell wall material (polysaccharides), which are the same in the fruiting body and the mycelium, but also all the extra-cellular compounds with their wide ranging health benefits.

Even ten years ago, modern cultivation methods capable of producing fully potentiated Ganoderma Lucidum had not yet been perfected. Following the tradition of over five millennia, most companies would grow or buy the fruiting body, make it into a tea, then let it air dry (spray drying was perhaps the only modern innovation added more recently to the process).  This became what is known as a “hot water extract”.

Many falsely claim that the hot water extraction process still provides the best, most bioactive form of Ganoderma Lucidum.  Reason alone tells us this is nonsense and science provides the validation.  We all know that extreme heat destroys many bioactive compounds.  Furthermore, the concept that extracts are better than anything else is yesterday’s science and does not reflect today’s state-of-the-art knowledge. These “hot water extracts” are certainly better than trying to digest Ganoderma Lucidum’s hard wood-like fruiting body, but the extraction process entirely misses the potential health benefits of the extra-cellular compounds.

Some companies simply cultivate the mycelium. This can be a better choice than using hot water extracts from the fruiting body if and only if the mycelium is grown in solid substrate.  Furthermore, mycelium products can be problematic and are not generally produced according to strict GMP standards.  In fact, most mycelium products contain up to 70% of unconverted substrate – so only 30% of what the consumer buys genetically qualifies to be called Ganoderma Lucidum.

Thanks to the modern advances in 21st Century American biotechnology, it is now possible to grow Ganoderma Lucidum under controlled laboratory conditions – a form of Ganoderma Lucidum that is hundreds of times more potent than any Ganoderma Lucidum grown in the wild and far more potent than the best Ganoderma Lucidum cultivated on logs or grown in sterilized compost.

Introducing Ganoderma 365
Fully Potentiated Ganoderma Lucidum

GanoLife is the leader in producing the highest quality Ganoderma Lucidum and we have the scientific validation to prove it.  In developing our production processes, we looked long and hard at the science.  After considering all of the evidence, GanoLife Scientists developed special growing methods that would maximize the production of targeted bioactive compounds throughout the full life cycle of the fungi and forged the concept of fully potentiated Ganoderma 365.  GanoLife developed custom growing chambers, strictly defined certified organic growth substrates (no sawdust, straw or compost is ever used) and specially modified growth parameters like climate control, light cycles, and air quality.  By controlling each and every aspect of the growth cycle, GanoLife is able to produce the best quality, the most potent and the most consistent Ganoderma Lucidum available anywhere in the world, while ensuring against all possible contamination of heavy metals, pesticides, herbicides or insect residue so common in other Ganoderma Lucidum products produced in less exacting regions of the world.

One great advance GanoLife made to the science of mycology is our patent-pending, proprietary growth chambers that allow us to bio-convert all of the raw substrate material into fungal tissue and extra-cellular compounds (over 99.99% conversion). By the time of harvest, we have obtained all of the different health-giving aspects that Ganoderma Lucidum presents throughout its entire life cycle and call the fully potentiated result Ganoderma 365!

GanoLife’s Quality Control is the best in the industry. Our Ganoderma Lucidum is third-party DNA certified through the U.S. National Institutes of Health – National Center for Biotechnology Genebank (NCBI).  All required chemical and microbial assays are performed by independent FDA certified, third-party analytical laboratories. A Certificate of Analysis and a full chemical and DNA profile is provided with each lot. While most manufacturers test only for the few items required by the FDA such as the total microbial plate count and e-coli content, at GanoLife we analyze for a comprehensive array of substances. This includes more than 90 heavy metals, a full polysaccharide profile including beta glucan, identification of heteropolysaccharides and residual starches, all microbial and sterility tests, plus any specialized analysis that may be required. Our extensive identification protocols, GMP processing and detailed documentation help make GMP processes and certifications go much smoother. With a production capacity of nearly 200 tons per month, we will never run out of Ganoderma Lucidum.  We also utilize  micronization technology to reduce Ganoderma Lucidum down to less than one micron in particle size to ensure maximum bio-availability in a fully water soluble form.

If you want the best Ganoderma Lucidum available, GanoLife is the new gold standard and by far the best choice —100% Certified Organic by USDA and EU, 100% Certified Kosher by Star K, and 100% Satisfaction Guaranteed. It does not get any better than this. Why risk your health or reputation on products containing questionable imported raw materials, when the best quality is made in the Americas with all-American ingredients.   In every way imaginable, we have redefined Ganoderma Lucidum and we are GanoLife!


NOTE: Under US FDA law, it is illegal for a manufacturer to make any medical claims for health supplements.   All statements made by GanoLife are intended for informational purposes only. These statements have not been evaluated or approved by the FDA, and our products are not intended to diagnose, treat, cure or prevent any disease.